Table 1 Summary of clinical and pathological findings
Heifer number | Clinical signs | Macroscopic findings | Histopathological findings |
|---|---|---|---|
1 (†54 dpi) | None | None | None |
2 (†25 dpi) | Cough, fever | Fibrous adhesion: At right diaphragmatic lobe | Necrotizing and suppurative broncho-interstitial pneumonia, entire lobuli affected, extension of necrosis to adjacent lobuli, oedema, fibrin exudation and suppurative inflammation in interlobular septae, fibrin thrombi in interlobular lymphatics, beginning fibrosis at margins of lesions |
Sequester: Seven (1–2 cm in diameter) in right and left diaphragmatic lobe | |||
3 (†53 dpi) | None | Fibrous adhesion: Between left middle and caudal lobe Between caudal lobe and parietal pleura | Necrotizing and suppurative broncho-interstitial pneumonia, entire lobuli affected, thick, cell rich fibrous connective tissue capsule formation in interlobular septae with lymphocytic infiltration |
Sequester: Two (0.5 and 5 cm in diameter) in left middle and caudal lobe One (3 cm in diameter) in right diaphragmatic lobe | |||
4 (†54 dpi) | Cough | Fibrous adhesion: Between left caudal lobe and parietal pleura | Necrotizing and suppurative broncho-interstitial pneumonia, entire lobuli affected |
Sequester: One (3 cm in diameter) in left caudal lobe | Thick, cell rich fibrous connective tissue capsule formation in interlobular septae with lymphocytic infiltration | ||
5 (†55 dpi) | Cough | Fibrous adhesion: At right caudal lobe | None |
6 (†55 dpi) | Cough, fever | Fibrous adhesion: Multiple at all lung lobes | Necrotizing and suppurative broncho-interstitial pneumonia, entire lobuli affected |
Sequester: Seven (3–12 cm in diameter) in all lung lobes | Thick, cell rich fibrous connective tissue capsule formation in interlobular septae with lymphocytic infiltration |