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Selective Adherence of Erysipelothrix Rhusiopathiae to Heart Valves of Swine Investigated in an in Vitro Test

Selektiv adhesjon av Erysipelothrix rhusiopathiae til hjerteklaffer fra gris belyst i et in vitro-forsøk

Abstract

An in vitro test for the adherence of microorganisms to epithelial surfaces was performed in an attempt to illustrate the initial steps in the establishment of infectious endocarditis. Preparations of fresh heart valves of swine were incubated in suspensions of Erysipelothrix rhusiopathiae. There was a significant difference (P < 0.01) in the degree of adherence between the 5 strains of E. rhusiopathiae investigated. The highest degree of adherence was found in an isolate from an endocardial vegetation and in a strain labelled type A1, both originating from swine. Scanning electron microscopy showed the microorganisms distributed on the endocardial surface and in large numbers at the base of the chordae tendinae.

Sammendrag

Det er utført et in vitro forsøk for adhesjon av Erysipelothrix rhusiopathiae til overflaten av hjerteklaffer for å illustrere det innledende trinn i utviklingen av infeksiøs endokarditt. Ferskt materiale av hjerteklaffer fra gris ble inkubert i oppslemminger av bakterier. Kimtellinger viste en signifikant forskjell (P < 0,01) i adhesjon mellom 5 E. rhusiopathiae-stammer av forskjellig opprinnelse. Størst adhesjon viste en stamme isolert fra en endokardial påleiring og en type A1-stamme, begge isolert fra gris. I scanning elektron mikroskopi sås mikroorganismene spredt over den endokardiale overflate og i størst antall ved basis av chordae tendinae.

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Bratberg, A.M. Selective Adherence of Erysipelothrix Rhusiopathiae to Heart Valves of Swine Investigated in an in Vitro Test. Acta Vet Scand 22, 39–45 (1981). https://0-doi-org.brum.beds.ac.uk/10.1186/BF03547204

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