Chronic pneumonia in calves after experimental infection with Mycoplasma bovis strain 1067: Characterization of lung pathology, persistence of variable surface protein antigens and local immune response

Table 3 Distribution of M. bovis antigens in lungs of 8 experimentally inoculated calves

Location¹	mAb pool²	mAb 1A1³	mAb 1E5⁴	mAb I₂⁵
Macrophages^a	8/8^a;8/8^b	8/8^a;8/8^b	0/8^a;6/8^b	NR^a;5/8^b
Exudate in lumina of large airways	8/8^a;8/8^b	6/8^a;6/8^b	0/8^a;4/8^b	NR^a;4/8^b
Epithelial surface of large airways	6/8^a;6/8^b	4/8^a;4/8^b	0/8^a;2/8^b	NR^a;0/8^b
Alveolar surface	3/8^a;3/8^b	1/8^a;1/8^b	0/8^a;2/8^b	NR^a;0/8^b
Caseous necrosis	2/2^a;-^c	2/2^a;-^c	0/8^a;-^c	NR^a;-^c

^1aAlveolar macrophages, macrophages in alveolar septa and macrophages within lumina of bronchi and bronchioli.
^2a,3a,4a Number of positive calves/number of calves examined (paraffin sections).
^2b,3b,4b,5b Number of positive calves/number of calves examined (frozen sections).
^2c,3c,4c,5c Necrotic lesions were not present in lung samples, from which the frozen sections were prepared.
^5a No reactivity.

ISSN: 1751-0147