Table 2 Ventilation and blood gases (n = 7)
From: Effect of sedation with detomidine and butorphanol on pulmonary gas exchange in the horse
Unsedated | Detomidine | Detomidine-butorphanol | GLM – ANOVA | ||
|---|---|---|---|---|---|
RR | Breaths/min | 16 ± 3 | 12 ± 5 | 10 ± 1* † | p = 0.032 |
V E | ml/min × kg | 163 ± 36 | 157 ± 42 | 114 ± 24* | p = 0.031 |
VT | ml/kg | 8.6 ± 1.8 | 10.6 ± 3.5 | 10.1 ± 2.4 | NS |
PaCO 2 | kPa (mmHg) | 5.9 ± 0.3 (44.3 ± 2.2) | 6.1 ± 0.2* (46.1 ± 1.8) | 6.4 ± 0.3* † (47.7 ± 2.1) | p < 0.001 |
P(A-a)O 2 | kPa (mmHg) | 0.5 ± 0.4 (4.1 ± 2.8) | 2.2 ± 0.7* (16.6 ± 5.4) | 2.3 ± 1.3* (17.2 ± 9.7) | p < 0.001 |
PaO 2 | kPa (mmHg) | 12.8 ± 0.7 (95.7 ± 4.5) | 10.8 ± 1.2* (80.7 ± 8.7) | 10.6 ± 1.4* (79.2 ± 10.6) | p < 0.001 |
PvO 2 | kPa (mmHg) | 4.3 ± 0.3 (32.5 ± 2.6) | 3.5 ± 0.5* (26.0 ± 3.5) | 3.6 ± 0.2* (27.0 ± 1.7) | p < 0.001 |
VO 2 | ml/min × kg | 3.2 ± 0.5 | 2.4 ± 0.6 | 2.9 ± 1.0 | NS |