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Table 1 Number of dogs participating in a clinical controlled therapy trial of 80 dogs with different degrees of canine hip dysplasia. The dogs were randomly assigned to receive either gold bead implantation or placebo in a blinded 6-month study. The dogs in the placebo group were thereafter offered a crossover to gold bead implantation, and all dogs were followed in an open trial for another 18 months.

From: Stratification, Blinding and Placebo Effect in a Randomized, Double Blind Placebo-controlled Clinical Trial of Gold Bead Implantation in Dogs with Hip Dysplasia

 

Double blinded controlled clinical trial over six months

Open clinical trial Follow up 18 months

Treatment

Completed no. of dogs

Drop out

Withdrawal

Completed no. of dogs

Drop out

Withdrawal

Gold

36

2

0

32

2

2

Placebo

42

0

0

7

2

0

Gold, follow up period

*

*

*

29

1

3

Total

78

2

0

68

5

5

  1. * = not applicable