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Table 1b Virological and serological findings in vaccinated calves during acute outbreak of respiratory disease in herd A (a) and herd B (b). Nasal swabs were taken at the acute phase (20/26 Jan) and paired serum samples were taken at the acute phase and one month later (18/19 Feb). The nasal swabs were analysed for the presence of bovine respiratory syncytial virus (BRSV), bovine corona virus (BCV) and parainfluenza-3 virus (PI-3) antigen (Ag) by ELISA. Serum samples were analysed for the presence of antibodies against BRSV (IgM, IgA, IgG1, IgG2 isotypes) and neutralising antibodies (SNT), BCV (Ab) and PI-3 (Ab). Significant change in antibody titers were defined as either sero-conversion (from 0 to any titer) or at least four-fold rises. Dead: The calf died between the two sampling dates. NA: NOt applicable. * Insufficient amount of sample for testing.

From: Bovine Respiratory Syncytial Virus (BRSV) Pneumonia in Beef Calf Herds Despite Vaccination

 

BRSV Ag

BRSV-IgM

BRSV-IgA

BRSV-IgG1

BRSV-IgG2

BRSV-SNT

Calf #

26 Jan

26 Jan

18 Feb

26 Jan

18 Feb

26 Jan

18 Feb

Rise

26 Jan

18 Feb

Rise

26 Jan

18 Feb

Rise

1064/5

0

0

0

*

40

* ≥ 1280

10240

NA

*

5120

NA

64

2048

YES

2535/5

0

0

Dead

80

Dead

2560

Dead

NA

80

Dead

NA

2048

Dead

NA

2537/5

0

0

0

0

0

320

320

NO

0

320

YES

128

256

NO

642/5

0

0

Dead

0

Dead

1280

Dead

NA

0

Dead

NA

64

Dead

NA

829/5

0

640

0

80

20

640

160

NO

20

160

YES

64

32

NO

1057

0

0

0

0

0

1280

2560

NO

0

640

YES

256

128

NO

821

0

0

Dead

80

Dead

1280

Dead

NA

20

Dead

NA

2048

Dead

NA

799

0

0

Dead

0

Dead

320

Dead

NA

0

Dead

NA

64

Dead

NA

795

0

320

Dead

80

Dead

5120

Dead

NA

0

Dead

NA

1024

Dead

NA

1317

0

0

0

0

20

640

2560

YES

20

160

YES

8

148

YES

 

BCV Ag

BCV Ab

PI-3 Ag

PI-3 Ab

      

Calf #

26 jan

26 Jan

18 Feb

Rise

26 Jan

26 Jan

18 Feb

Rise

      

1064/5

0

*

≥ 25600

NA

0

*

0

NA

      

2535/5

0

6400

Dead

NA

0

0

Dead

NA

      

2537/5

0

3200

12800

YES

0

0

0

NO

      

642/5

0

800

Dead

NA

0

0

Dead

NA

      

829/5

0

800

≥ 25600

YES

0

0

8

YES

      

1057

0

1600

≥ 25600

YES

0

0

0

NO

      

821

0

6400

Dead

NA

0

16

Dead

NA

      

799

0

3200

Dead

NA

0

0

Dead

NA

      

795

0

3200

Dead

NA

0

8

Dead

NA

      

1317

0

12800

12800

NO

0

8

0

NO

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